JSGH-300水平式干法制粒機工作原理(Working Theory of Dry TypeGranulation Facility):
根據(jù)機械擠壓造粒工藝原理,將配置好的,具有一定結(jié)晶水的干粉狀或微細晶體狀原料,擠壓成薄片,后經(jīng)造粒系統(tǒng),通過篩網(wǎng)制成所需大小的顆粒。
原料可通過手工上料或真空上料機加入料斗,經(jīng)送料螺桿輸送和壓縮.被推至兩擠壓輥輪的咬入角:通過壓輥,將原料擠壓成薄片。物料所需的壓力通過液壓裝置線性傳送給壓輥,液壓裝置可保持一定的預壓力, 垂直排列的壓輥可保證物料密度的一致性。根據(jù)不同顆粒度要求,設備造粒系統(tǒng)中的篩網(wǎng)目數(shù)大小可相互更換。
According to the technical theory ofmechanical extrusion for granulation, a wel-prepared powdery or finely crystallinematerial with crystal water is laminatedand made into particles of required size bymeans of screen in the granulation system.
The material may be fed into the bucketby hand or vacuum feeder, conveyed andcompressed in the feed screw, and pushedinto bite angle of two extrusion wheels.The material is laminated by therollers.The pressure required by material islinearly delivered from hydraulic device torollers. The hydraulic device can maintaincertain pre-pressure and the verticallyarranged rollers can guarantee theconsistent density of According to different required grainmaterial.sizes, the screens with different meshes inthe granulation system can be interchanged.
JSGH-300水平式干法制粒機干法制粒優(yōu)點(Advantages of Dry TypeGranulation):
將粉體或微細晶體原材料直接制成滿足用戶要求的顆粒狀產(chǎn)品,無需任何中間體和添加劑,造粒后產(chǎn)品粒度均勻,堆積密度顯著增加,改善流動性,既控制'了粉塵飛揚,又減少粉料浪費。便于貯存和運輸,可控制溶解度、孔隙率和比表面積等。
本機在濕式造粒法中難生產(chǎn)的抗生物質(zhì)。膠囊填充用顆粒及制造藥片的造粒上能發(fā)揮很大的作用。
Powder or fine crystal can be directlymade into granules to the satisfaction ofusers, without requiring any intermediate oradditive. The granules have even grain sizewith considerably increasing bulk density.This can improve the fluidity, inhibit theraised dust and reduce the waste of powder.
It is easy to store and transport andallows the control of solubility, porosity andspecific surface area.The granulator generates the antibioticThe granulator generates the antibiotictype granulation. .type granulation. .It can play an importantrolein thein thethe granulation for pills.
JSGH-300水平式干法制粒機應用范圍(Applcability):
在制藥工業(yè)中,廣泛涉及到對各種活性的藥品原料以及-種或多種賦形劑的加工處理。這些原料藥大部分是細的粉末,并且這些粉末粒徑大小不一,密度不勻,流動性差,易分層。這些原料藥必須經(jīng)過制粒工藝處理.才能.被用于壓片、膠囊填充或其他藥物加工工序。干法制粒因其具有多種優(yōu)勢.特別適用于在濕.熱條件下不穩(wěn)定的藥物的制粒。
The pharmaceutical industry oftenprocesses the medicine materials of variousactivities and one or several excipients.Most of bulk drugs are finely powdery indifferent grain sizes, uneven density, poorfluidity and easy stratification. They must begranulated before being laminated, flled intocapsules or processed in other ways. Forits various advantages, dry type granulationis particularly suitable for the granulation ofdrugs unstable under wet and hot conditions.
JSGH-300水平式干法制粒機特別說明(Special Note):
在產(chǎn)品設計和生產(chǎn)過程中,我們遵循了美國FDA、GMP思想。任何一臺設備在生產(chǎn)過程中,皆具備GMP控制范圍;在設計過程中,任何一臺設備皆在GMP內(nèi)創(chuàng)新構(gòu)思。所有的非金屬材料均符合GMP &FDA標準。
送料量、壓力、壓輥間隙、片厚、整粒間.隙、片硬度等工藝參數(shù)通過邏輯運算、數(shù)理統(tǒng)計建數(shù)據(jù)模型,并形成科學系統(tǒng)關(guān)系。
In the machine design and .manufacturing process, we follow theFDA GMP idea. Any equipment in themanufacturing process has GMP controlrange,In the designing process, anyequipment is in GMP innovation concept.All non-metallic materials comply withGMP&FDA standards.
The process parameters such as feedamount,pressure roller gap, slicethickness,grinding gap and slice .hardness were established to formscientific system relationship throughlogical operation and mathematicalstatistics.
JSGH-300水平式干法制粒機設計特點(Design Features):
新型料斗設計,無堆料、積料、尾料。
伺服攪拌和伺服送料系統(tǒng),速度靈活方便設定,滿足不同物料流的平衡,送料更精準、均衡、平穩(wěn)、扭力更強。
根據(jù)物料特性,設計匹配單螺桿、雙螺桿型線和壓輥表面結(jié)構(gòu)(特殊表面處理,使粗糙度降低到0.1。減少黏輥和側(cè)封板磨損)。在線軸承潤滑;整粒部分溫度實時監(jiān)控;在位清洗功能;開門等有報警功能。所有傳動系統(tǒng)加正壓氣密封。片劑硬度檢測裝置。內(nèi)置式進口壓輥間隙位移檢測控制系統(tǒng),控制精度達到0.01mm。
三級整粒,實現(xiàn)逐級等比例破碎,整粒刀和整理網(wǎng)間隙可調(diào)。大大減少破網(wǎng)機率,提高一次成品率10 - 20%。液壓系統(tǒng)PID調(diào)節(jié)功能,精度達到0. 1Mpa。
主軸加粗,特殊材質(zhì)特殊工藝處理,防變形,防斷裂。壓輥與主軸特殊密封,杜絕冷卻水滲漏問題,避免通過主軸向箱體漏粉。
New style hopper design, no malerfal heaping and no tailmateral.Servo mbing and servo foodng system, the speed Is flexlble andoorvenient to set, to meet the balance of iferent material flow,material feeding is more accurate, bllanced, stable, and withstonger torque.Acoording to the material characeistics, designing and matchingthe proile of single screw or double screw and the surface shructueof rllrl could be customized. Special surface treatment will reducethe roughness to 0.1 and reduce the wearing of side saling plateand avold stcking matertals on the rlen.and avold stcking matertals on the rlen.on-line bearlng lubrication, On-line cleaningfunction(CIP), With alaming on the door openingAl trasmision systems with psitve pressure and air seal anddamage alam function. Slice hardness tsting deviceBult in dlearance displacement detection and control system forinlet press rller, the control aocuracy is up to 0.01mm
With 3 lewels grinding system, to achieve the level of proporfionalcrushing, the gap between the grinding knile and fisting meshcould be adlutable. Which will graly reduce the probailty olbreaking the sleve, improve the yeldof 10- 20%。Real- time monitoring of ginding temperatureHydraulic system PID adlusment function, precisionup to0.1MpaMain shalft thickened, special material special processing, anti-defomation, anti- fracure. The pressing oller and the shalt arespeilly sealed to prevent the lakage of coling water and awoid bythe main shalft frorm laking powder to the cabinet.
JSGH-300水平式干法制粒機技術(shù)參數(shù)(Technical Parameters):
生產(chǎn)能力
●批處理量:10000g
●連續(xù)生產(chǎn)能力: 300Kg/h
●可成型粒度: 0.2- 2mm
●操作系統(tǒng):西門子S7-200 SMART
●整機功率: 21Kw AC380,50HZ ( CN )
●擠壓輪規(guī)格:250 X 100 mm
●成型壓力: 100T
●攪拌轉(zhuǎn)速: 1-80轉(zhuǎn)/分
●送料轉(zhuǎn)速: 1-150轉(zhuǎn)/分
●擠壓轉(zhuǎn)速:1-28轉(zhuǎn)/分
●破碎轉(zhuǎn)速: 110轉(zhuǎn)/分
●制粒轉(zhuǎn)速: 1-150轉(zhuǎn)/分
●整機重量: 2000 Kg
●外形尺寸: 1300X 1200 X 1800 mm
●物料接觸部分材質(zhì): SUS 304 & 316L
●擠壓輪材質(zhì): 2Cr13、 3Cr13、 合金鋼
●與物料接觸部分密封材質(zhì):聚四氟乙烯
Production Capacity
●Batching:10000g
●Continuous producion capacity:300kg/h
●Grain size: 0.2- 2mm
●Operation system: Siemens S7-200 SMART
●Installation power: 21Kw ,AC380,50HZ ( CN
●Roll dimension: 250 X 100 mm
●Maximum forming pressure:100 T
●Scrapper rotational speed: 1-80r/m
●Screw feeder rotational speed: 1-150r/m
●Roll rotational speed: 1-28r/m
●Flake breaker rotational speed: 110r/m
●Fime granulator rotational speed: 1-150r/m
●Dead weight: 2000 Kg
●Machine dimension: 1300 X 1200 X 1800 mm
● Material: SUS 304 &316L
●Material of roller: 2Cr13、 3Cr13、 alloy steel
●Axial gasket in contact with product: PTFE